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Retired NBME 22 Answers

nbme22/Block 2/Question#22 (reveal difficulty score)
A 35-year-old man comes to the physician ...
Adenylyl cyclase ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: endo repeat

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 +12  upvote downvote
submitted by โˆ—osgoodschlatter10(41)
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heT oretecrp in unteiqso is a G nitopre tpcroere on hte aupttyiri s.sma hTsi wludo eb het HGRH rec.oertp heT HG rrceepto lliw be prntsee rnswamoted so htta HG elesrdea from hte triiatpyu anc bndi to it shte(e ear STAKJT/A oes)er.HHRrG tcp rertspceo rea ยฌsG t.erosrpec sThee errcepots rea buodn ta eth aubpshluiant- to PDG ni teh victiena e.ttsa enhW HGHR isbdn ythe ctaivedat hwen TPG htsatace to the utpabnusaihl- setad.ni dnA eyetrhb tmeooospr naedyl aelcysc ia.vst aPcGeityT is isorbnplsee to cvelea shit TPG fmor the paahl uinubts to ihwcst fo eth roe.epect ohTerfer a kcla fo eTPaGs aytitivc illw ernedr he sG ortrcepe ni a olngopedr no tatse ๏ƒ  Irescaned ivytctai fo nldAey alsyc.eC

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osler_weber_rendu  nBlliaitr aipatnoenxl +1
skonys  Is ti sles ubato RGHH vgihan a 3PI aosydecrn rgensamse or HG gisnu KJT/SATA nda rmoe hatt ew eerw pesuodps ot girneocze atth saG si a sG clupode eeorcptr nad sG rskwo ghtrohu elydlnyA ceyCsal. TPG dbisn to Gs adn smtu eb yehdsspprealohot yb a GeTaPs ot be eivnc.tidaa sBaecue eht mtrou escll clka tsih fniont,cu sG yasts hhptlydsopoaer and nelydlAy esalcCy onuetnsic ot eb caed?ivtta mI sjtu fneocuds on if nogkwni het doscnyear seemangsr smtsyes vene ertamt ro fi aecoaylrmg si onhrtw ni as a atrrdcosit rfom het irtnfmnooia driop.edv +1
weirdmed51  GH โ€™desnto vhae 3PI snerm,sgee ti sha MAPc +
weirdmed51  HRHG * (rros)y +

This is really helpful in explaining why the question is NOT asking about growth hormone receptor

+/- qfever(67)

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 +8  upvote downvote
submitted by โˆ—hayayah(1212)
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rtohwG hmeorno esgrinael oohmner tsca vai cGul-poed reeoscrpt. G loudepc rpereocst dene TGP to mobeec aticavdet nda PsTGea ot eeobmc ttvniadacie.

oN GaePTs- t;--&g lihcnoracyl ceitav thrgwo hoernmo gaeenlrsi rmheono rotpecre -&;-gt tcoansnt iitnvctaao fo eallndyy cylecas / cAPM wphyata nda lreseea fo gwrhot h.mnroeo

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mcl  hisT eufgir si sulfeu a-5-obtnp1212sp0af7razew2-./ic8e29m0decnd27hi.lu.su842efbda115/7ti/gid.44s0:6e5/0g6336s70mog1cue38aFsr-/-a600-f/ep +1
mcl  0sng2-0ai2t6s8]enoraw/3ccult/0bsfh8dF7emgr321ei1.l6-b-[eosm6k0ee1-1p:if2ueu/-dp1i604is5d.27.f4387-5aaa2)09a/(nz5g/dpc47/0. +
meningitis  How ddi uoy okwnk ti wsa RHGH dna not GH resp?e +4
meningitis  vdenemnr;i I ujst ared wdon owle.b nahTk yuo +19


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 +0  upvote downvote
submitted by goldenwakosu(7)
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yhW is het nseawr laeyylnd casy?lce I edookl in AF nad I swa that GH sseu hte 2JA/TKSTA phaawty dna that -1GFI uess hte MAP Knesia atpwh.ay oNt srue who lynyaeld lecysac pyasl noit .this

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pug_sheen  I hktni ehyt ear lkating uaotb hte HRHG rroeptec on tsohsprmo,ato chwhi rsowk hhutgro eth PAcM ayh.pawt +
staygoodpupper  I โ€™notd knwo who it aelerst ot IG1H/GF- ni ,crltiaprua utb het nqsituoe asid ehert wsa a moitntua ni the lhapa sbitnuu of Gs, wichh itvaeacts nlyyedal csec.lya +3
kash1f  I ergea eth attenpi does vahe yoagmArcle, tbu in the sutieqon ti aeldkt tboau woh het ttaeipn ahd a miutoant ahtt devtrneep eht ePasTG tiyictva of s.aG oS Gs ouldw eb aeeovvirct --> sseecx ynayldel yceclsa +31
hyperfukus  ghu i saw os tixeced oto cb i gohthut i ebremreemd jka tsat apfileic +3
skonys  sont'eD RHGH tac hrghuto na PI3 oraysecn mssar?egne +
xmen  het rtumo stesreec .HG HG act iav a KAJAS/TT a BPwahy.ttu teh GH notreisce si sdemlatuti vai a HRGH gthhrou a sG. Tshi sG in this osut'mr cslel si tmateud dna is nraetnlpemy caif.t os PcAM iwll .encersai +1
weirdmed51  nyk@sso HRGH works vai cAMP +
kcyanide101  GnRH is PI3 --- mRembere OTAG H?GA HRHG is CMPA eeemrrmb LATF CMAhP +


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