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nbme24/Block 3/Question#43

A 35-year-old woman with a long-standing history of ...

Infiltration of lymphocytes and monocytes

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 +3  upvote downvote
submitted by neonem(298),

Histoplasma can act like TB and cause cavitary lesions and calcified nodules with fibrotic scarring. In general, fungi are combatted by lymphocytes and macrophages, not eosinophils or neutrophils.

 +1  upvote downvote
submitted by yex(22),

This also refers to chronic inflammation & granuloma formation.

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submitted by dragon3(7),

Can anyone explain why bacteria is neutrophils, viral/fungi are lymphocytes? I know this is a fundamental concept...

lolmedlol  i think neutrophils (in addition to lacking granzymes and perforins which are used to kill viruses and fungi) dont recognize intracellular things; viral antigens needs to be processed and presented on an MHC for the lymphocytes to recognize +1  
usmile1  also neutrophils are only seen in acute inflammation. This pt has longstanding inflammation which is associated with monocytes, lymphocytes, macrophages, plasma cells. +  
usmlecrasherss  Neutrophil come and goes quick like day or two , after that rest of immune cells take care +