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Retired NBME 24 Answers

nbme24/Block 1/Question#40 (reveal difficulty score)
A 26-year-old man and his 25-year-old wife ...
One in four will have 25% β-globin function and may require occasional transfusions 🔍 / 📺 / 🌳 / 📖
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 +31  upvote downvote
submitted by ∗brethren_md(105)
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kaMe a enutntp suaeqr iwth a oscsr of B B+ dna B 0B; B+ neseetrpsr 50% ncinutof hewli B0 tsepnsreer 0% (nlul) cifnnuot. So in tish ,ecas the ushabdn dwulo hvea a B 0B pyeotneg lewih het wefi ahs a B +B oete.pngy

rssCo fo ehets tow wlli truels ni het goflwilno eysog;pnet ,BB ,B0B ,+BB B0B+ BB = %010 tncoi,nuf BB+ = 5%7 nc,ufnoit 0BB = 05% icn,nufot +BB0 = 2%5 niocftnu

oS eth rnasew lliw eb 1 ni 4 veah a 2%5 ofucntni iengv eth se.eoypgtn

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tyrionwill  woh tboau eht cecioh fo D: 1 in 4 aehv 5%0 toifu,cnn ihhwc si rt.eu hllsa 0%5 tcniounf sneed iantnurs?ofs +
tyrionwill  nI ,AF it iesfned teab mlaashiseat into irnmo 2AHb( 5%).tg&;3 nad mrjao toh(b FbH nda H2bA go furerth ,pu) nda hte ramoj eedsn riusfnostna qfeuylnt.er wHo acn we ekat itsh ilasonsfcaitci seadb uonp ttiivanque yaw lkie in tsih uqe?tinso hwo hucm neeategrpc fo ncuoitfn felt deos ont deen a euretqfn ntsfuonirs?a +
azibird  D syas eno in W,TO tno eon in UORF. +6
hemehero  Is ethre a ywa ot wnko that +0BB liwl = 5%2 utn.nciof I asw ksutc teewenb %52 iuncotfn nda 10% ufnicon,t tub oc'tdlun iufgre uot ohw ot oeanrs twbeeen eht tow of me.th +3
neil_simmons  Teh nusieqto yssa the ormeht has a matoutni nwkon to ascue 05% caesdere ni -ibengtalbo geen fcoiuntn fo noe el.leal So if eno allele is iwrkgno at 5%0 +()B dan eth ehtro lallee is ginwokr at 0% ,0()B hnet ttha udlow mnea that plrtaiacru ste fo eeallsl would ncouitfn ta 5.%2 +2
twich22  eTh yeK erhe si the oawnm hsa %50 descraee ni otuinfcn fO" eno l.aelel" Its a tsdipu yaw to rodw t,i But ti neams ahtt eno lleela orskw at 50%, icwhh oluwd eb B+. oS fi uoy evha a B0/B+ f,grofinsp eth 0B vgeis 0% dan het +B owksr at %50 tacic,apy so you noly aehv %52 of nolarm. +
murad  emso one ipeanlx tsih to me el,psae woh moec fi het mthoer iwht his gnypeeto BB+ has 0%5 ftnnuioc fo neo lelal.e wihel if ew etg hre pinffrsgo nupnet usraqe ew sodircen teh eno ahtt ash the esma ptoneyge as reh B+B fo ianvhg 57% ni?fo?cnut +



 +3  upvote downvote
submitted by ∗an_improved_me(91)
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I efel iekl sit heest niskd fo oesquntis atht llayre kmea a etraesttk- sd.eeucc uoY lucdo ehva detisdu ryou wlohe fiel fro epSt 1, dna .omethcn.e. up asnaitg a qnestuio ielk ht.is sIt etsgnti opstcecn ttha 'royue maailfri wthi ..(ge -eealitamathasBs, )ie,tcengs but in a yaw htta n'tsi hionmtgse 'oyud ever itdleyrc rn.lea oY u evah to atsy lac,m lzaaney thaw oyu nkw,o twah hte iueqntos si iask,gn craeet a asttgyre to e,rasnw adn kloo at hwihc snaerw si .btes

I vyne smoe fo ou!y!

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 +1  upvote downvote
submitted by ∗medstruggle(21)
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athWs hte ferneifecd btewene uoes“zehtrygo nllu ittuonam ni B olignb ne”eg and yzeeohgruost“ otnutaim wnkno ot cusae 50% eeracsed ni B gonbli eeng ncfitoun fo neo eellal”?

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welpdedelp  I pendirreett llun"" sa imngnea ullf otedlien ihewl eht rtheo tehoysuerogz auostmnti asw olyn a 05% casereed ni teh .tifnounc neO hldic wuldo niietrh 1 unll tounmtai dna 1 0%5 ,untoaitm wihch wduol avele htme thwi a %52 oliactnunf g.ene +18
j44n  A tahl si teh oeliednt, B ltha si aouitstmn on etmroospr or lipecs ei.sst +



 -1  upvote downvote
submitted by mynamejeff(0)
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I knith E si osla elab.i..v 41/ si BB/ nda thaerno 41/ si B/+B . heT /BB+ si aseBlt-aamish rniom rhwee B hacin si durpuenocrdde c(uisntnfo mlal)yorn dna is yluslua i,otmacmapyts epr FA 0220( g.p .418)

hhs?tuogT

Al,os my ginntadnudesr on eBatmiasasl-h rfmo r.D rSttaa adn siftr aid si htta 'tsi ton tse ni seton htta +B is 50% p.odocnriut It sseem ot ayrv.

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syringomyelia1  E ssya 2/1 ont 4/1 +1



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