NBME 24 One in four will have 25% β-globin function and may require occasional transfusions (NBME Answers)

Retired NBME 24 Answers

nbme24/Block 1/Question#40 (reveal difficulty score)
A 26-year-old man and his 25-year-old wife ...
One in four will have 25% β-globin function and may require occasional transfusions 🔍 / 📺 / 🌳 / 📖
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+31 upvote downvote
submitted by ∗brethren_md(105)

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kaeM a eunttpn eurqas itwh a ocrss fo B B+ dan B 0;B +B tsrenpsere %05 outnncfi iwhel B0 steernpesr %0 (nul)l uointc.nf So in tish eca,s het uanbdhs uowdl heav a B B0 neegypot ilewh the wfei ash a B B+ oepetn.gy

Csosr of eshet wot illw slreut in the oifogwlnl et;gysenop B,B BB,0 BB,+ 0+BB BB = %001 citf,nonu B+B = 7%5 cn,nfiout B0B = %50 ifuntcn,o 0BB+ = 25% otcifnun

So eht wernas iwll eb 1 in 4 hvae a %25 cuntnifo igenv eth yeont.espg

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tyrionwill ohw btuao eth echoic fo :D 1 ni 4 vahe 5%0 nfutoic,n whhci is etu.r hllsa 5%0 intfuonc eesnd stosirnfanu? +

tyrionwill In F,A ti ndesefi etba tamihaessal toin niomr Ab(2H 3.;g%&t5) and rmajo bht(o FbH nad AHb2 og efurthr )pu, nad eth armjo deens snoustrnifa neyqetufl.r owH acn ew atke ihst onssaictlifcai bdsae opun nqtatiuiev yaw ielk in stih qni?tueos how uchm etrpgeacen fo fntucnoi eltf esdo otn need a ufeenqtr nsfiuortsn?a +

azibird D asys noe ni WO,T otn oen in F.ROU +6

hemehero Is rhete a way to ownk ahtt +0BB will = %25 ocfntiun. I asw tuksc eebwent 5%2 inutcfno dan 0%1 nufctin,o utb out'nlcd iergfu tou woh ot roasne ntweeeb het wto fo .etmh +3

neil_simmons The sntoqeui sysa hte homter sah a mnoiautt wonnk to ucsae %05 rcaeeesd in og-bnitabel geen nicuotfn of one lelel.a So fi oen elaell si iowknrg ta %05 )+B( dan hte rhote elelal si nwikogr ta 0% ,)(B0 hetn thta uwold nema tath apirltucar set of leslela oulwd cfntnuoi ta .25% +2

twich22 The Kye eher si eht monaw sha 5%0 radseeec in ntifuocn "fO eno l"alel.e sIt a tispud ayw ot odwr t,i tuB it nemsa hatt eno eellal skwor ta 50,% which lowdu eb B.+ So if yuo evha a B/+0B in,fsrgofp hte B0 egvis %0 dna het B+ ksrow ta %50 pa,yiccta so uyo lony hvea 52% fo lronam. +

murad eoms eon nlpxiae stih ot em lees,ap how coem fi the hretom hwit ihs oyptegne B+B sah 05% tcifunon of noe alll.ee wehil if ew tge her fgiofsrnp nuntpe seruaq ew nidrcsoe the eno hatt sha teh aems pyegonet sa ehr BB+ of ihvnag 75% utnfoni??c +

+3 upvote downvote
submitted by ∗an_improved_me(91)

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I leef liek sti seeth dnisk fo tsesonuiq thta rayell amke a sr-eetktta cee.dcsu oY u dlcou eavh deiutsd uyro hoelw leif fro epSt 1, dan to..ceh.nem pu aiatnsg a untqeios liek st.hi sIt nisgtet cscneopt taht ore'uy liraaifm itwh .e(.g ie,haamaaltBss-te ),ecsgient utb ni a ayw that 'tins hsenmigto yduo' evre irtdcely .aelnr o Yu ehav ot ayts macl, zeanlya thwa you n,kow htwa eth qnotsuei si sn,gika rtecea a tygrstea ot a,rsnew dna kolo ta ichhw waersn is tebs.

I nyve mseo of u!yo!

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+1 upvote downvote
submitted by ∗medstruggle(21)

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atWhs hte redenfefci etwbene “gyehuooszrte lnul umntaiot in B blgoin ne”ge nad sreze“ytouogh taountmi kwonn to useca 5%0 sedarcee ni B inlogb egne ufnntioc fo neo leale?l”

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welpdedelp I rpridttneee nlul"" sa egiamnn flul ldotenie ilehw eth roeht eorzeguhstyo samuintot saw olyn a 50% ecsrdaee in eht tc.fouinn One lcihd luodw heiirtn 1 null iotnamtu dan 1 50% iatmu,tno hciwh ulowd vlaee mteh hiwt a 52% nunicltoaf eeng. +18

j44n A laht si hte indoe,tle B thla is noiaumtst no pmrrtooes ro eislpc ei.tss +

-1 upvote downvote
submitted by mynamejeff(0)

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I knhti E is losa a..e.bvil 1/4 si BB/ adn tahnroe 4/1 si B/+B . The B+/B si ssaaam-Bithel onmir werhe B ichna is uepeudroncrdd onfius(cnt malnyl)ro nda is yllsuua patmtos,ymaic erp FA (0022 .pg .)481

gut?hhsoT

o,Asl my ugsndtdrainne no -lmseahaBitsa rofm rD. tatarS nad itrfs dia is tath sit' tno tse in esont htta +B si 5%0 nicurdopto. It esesm to r.vya

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syringomyelia1 E ssya 12/ ton 41/ +1

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