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NBME 23 Answers

nbme23/Block 3/Question#40

A 38-year-old woman with hypercalcemia, ...

Area labeled ‘B’ (Proximal convoluted tubule)

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submitted by mcl(377),

FA 2019 P 573 - The only part of the nephron that first aid says has an effect on PO4 3- is PCT.

motherfucker  PTH inhibits na/PO4 cotransport -> PO4 excretion +2  




Early PCT—contains brush border. Reabsorbs all glucose and amino acids and most HCO 3 – , Na + , Cl – , PO 4 3– , K + , H 2 O, and uric acid. Isotonic absorption. Generates and secretes NH 3 , which enables the kidney to secrete more H + . PTH—inhibits Na + /PO 4 3– cotransport = Increased PO 4 3– excretion