Most human cancers are d/t a loss of function of TP53 gene.
Associated neoplasms in Li-Fraumeni syndrome. Sarcomas, breast cancer, brain tumors, adrenocortical carcinoma, leukemia
Other way to get this question is by eliminating other options -- this figure is useful in listing some mutations and associated cancers.
Li Fraumeni, Tp53 mutation. SBBLA cancers
sarcoma
brain
breast
lung
adrenal
submitted by โneonem(629)
Sounds like a case of Li-Fraumeni syndrome - since p53 is a tumor suppressor for a bunch of cell types, mutations in this gene (as in LFS) result in a myriad of familial tumor types.