1. platelets in the blood begin to stick to the injured site.
2. This activates the platelets, causing a few things to happen.
3. They change into an amorphous shape, more suitable for clotting, and they release chemical signals to promote clotting.
4. This results in the activation of fibrin, which forms a mesh and acts as "glue" to bind platelets to each other.
5. This makes a clot that serves to plug the break in the blood vessel, slowing/preventing further bleeding.[5][6]
   
   

1. This happens through the process of phagocytosis, where white blood cells "eat" debris by engulfing it. 
2. Platelet-derived growth factors are released into the wound that cause the migration and division of cells during the proliferative phase.
   
   

1. In angiogenesis, vascular endothelial cells form new blood vessels.
2. In fibroplasia and granulation tissue formation, fibroblasts grow and form a new, provisional extracellular matrix (ECM) by excreting collagen and fibronectin.
3. Concurrently, re-epithelialization of the epidermis occurs, in which epithelial cells proliferate and 'crawl' atop the wound bed, providing cover for the new tissue.
4. In wound contraction, myofibroblasts decrease the size of the wound by gripping the wound edges and contracting using a mechanism that resembles that in smooth muscle cells.
5. When the cells' roles are close to complete, unneeded cells undergo apoptosis.

Maturation (remodeling): During maturation and remodeling,

1. collagen is realigned along tension lines, and cells that are no longer needed are removed by programmed cell death, or apoptosis.