NBME 21 Tubulin polymerization stabilization (NBME Answers)

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Retired NBME 21 Answers

nbme21/Block 2/Question#38 (reveal difficulty score)
A 63-year-old man with bladder cancer starts ...
Tubulin polymerization stabilization 🔍 / 📺 / 🌳 / 📖
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submitted by ∗dr.xx(176)

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Paclitaxel stabilizes the microtubule polymer and protects it from disassembly. https://en.wikipedia.org/wiki/Paclitaxel#Mechanism_of_action

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submitted by ∗amirmullick3(76)

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Just remember "Taxes stabilize society." FA2019 Page 433

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submitted by swandy(3)

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Drugs that act on microtubules may be remembered with the mnemonic "Microtubules Get Constructed Very Poorly":

M: Mebendazole (antihelminthic)

G: Griseofulvin (antifungal)

C: Colchicine (antigout)

V: Vincristine/Vinblastine (anticancer)

P: Palcitaxel (anticancer)

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