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NBME 19 Answers

nbme19/Block 3/Question#40

25 yo woman requests prenatal diagnosis at 12 weeks gestation

Chorionic villi sampling

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The stem states that the mother is 12 weeks gestation. CVS is performed 1st trimester, usually b/t 10-14 weeks gestation according to Up-to-Date. Amnio is performed after 15 weeks. From Up-to-Date: “Amniocentesis should be performed after 15 weeks of gestation because earlier procedures are less likely to be successful, are associated with higher rates of cell culture failure, and carry greater fetal risks.”