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Retired NBME 17 Answers

nbme17/Block 1/Question#20 (reveal difficulty score)
A 24-year-old man with a history of ...
480 ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: carrier_mediated

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 +9  upvote downvote
submitted by compasses(14)
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total concentration = 0.30mg/l x 200L = 60mg he took the drug 6 hours ago @ t-half of 2 hours 6hrs==60mg 4hours==120mg 2hours==240mg 0hours==480mg

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 +3  upvote downvote
submitted by โˆ—aoa05(34)
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Q46: half life (2 hrs) is the time it take for the drug concentration to half.ย  Since the time course is 6 hours after injection, 3 half-lives have passed.ย  The concentration 3 half-lives later is 0.3 mg/L.ย  This means at the time of injection, the concentration should be 0.3x2x2x2 = 2.4 mg/L.ย  Utilizing the formula mass/volume = concentration, mass (what the question is asking) = volume x concentration = 200L x 2.4 mg/L = 480 mg.

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