I swear this changes on who you ask. I've seen it as either Isoniazid or Isoniazid + rifampin.
EDIT: 2 answers are correct here (thanks NBME!)
Per CDC
"As of 2018, there are four CDC-recommended treatment regimens for latent TB infection that use isoniazid (INH), rifapentine (RPT), and/or rifampin (RIF). All the regimens are effective."
letsdothisYes, I was going to say the same thing. Per uworld, you can do dual treatment with rifampin with isonizid for 4 months. +2
yb_26isoniazid+rifampin is not an option for latent tuberculosis. This combination is used for 4 months after RIPE regimen therapy of active tuberculosis (rifampin+isoniazid+pyrazinamide+ethambutol). 3 treatment options for latent tuberculosis are 1) isoniazid+rifapentine+/-pyridoxine 2) isoniazid+/-pyridoxine 3)rifampin+2
Patient with a positive PPD (>10 mm in healthcare workers) who is asymptomatic and without CXR changes, most consistent with latent tuberculosis
Key idea: 3 treatment options for latent tuberculosis are (1) Isoniazid and rifapentine weekly for 3 months (2) Isoniazid for 6-9 months (3) Rifampin for 4 months
Key idea: PPD induration (NOT erythema) required for positivity depends upon patient risk factors with >5 mm being positive in patients with significant immunosuppression (HIV, organ transplant, immunosuppressant meds), recent contact with patient with active TB or patients with CXR findings consistent with TB // >10 mm being positive for patients from Tb endemic countries, IVDU, residents of high-risk settings (prisons, nursing homes, homeless shelters, etc.), children < 4 years old and patients working in mycobacterial labs // >15 mm in all patients
submitted by โseagull(1933)
I swear this changes on who you ask. I've seen it as either Isoniazid or Isoniazid + rifampin.
EDIT: 2 answers are correct here (thanks NBME!)
Per CDC
"As of 2018, there are four CDC-recommended treatment regimens for latent TB infection that use isoniazid (INH), rifapentine (RPT), and/or rifampin (RIF). All the regimens are effective."
https://www.cdc.gov/tb/topic/treatment/decideltbi.htm#:~:text=As%20of%202018%2C%20there%20are,All%20the%20regimens%20are%20effective.