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NBME Step 2 CK Form 8 Answers

step2ck_form8/Block 3/Question#4 (reveal difficulty score)
A 42-year-old woman comes to the physician ...
Serum antinuclear antibody assay ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: msk rheum

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submitted by โˆ—step_prep(148)
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  • Middle-aged woman with dry mouth, dry eyes, parotitis and dental cavities, consistent with Sjogren syndrome (although classically associated with anti-SSA/SSB, patients are also commonly ANA positive)
  • Sjogren syndrome:ย Onset in middle age, positive ANA, and often systemic manifestations (malaise, weight loss, joint pains, etc.)
  • Age-related sicca syndrome:ย Onset in elderly patient, especially women with diabetes or thyroid disorders, no systemic symptoms

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