Elderly patient with gram-negative bacteremia receiving gentamicin (aminoglycosides associated with acute tubular necrosis) who has developed oliguria and an AKI, most consistent with acute tubular necrosis
Acute tubular necrosis leads to pigmented granular casts
Causes of acute tubular necrosis: Sepsis, Aminoglycosides, ischemia/hypotension (spectrum of disease of pre-renal AKI), heavy metals, radiocontrast, ethylene glycol, rhabdomyolysis
azibirdYes. But I'm suprised no one has mentioned this yet, because it makes the diagnosis a lot more certain: Cephalosporins increase nephrotoxicity of aminoglycosides - FA 2020+1
submitted by โstep_prep5(246)
https://step-prep.org/tutoring/