Analgesic nephropathy (2/2 ASA, ibuprofen) can present with AIN, renal papillary necrosis, and ATN due to vasoconstrictive effects. Intrarenal pattern of injury (BUN/Cr<20) with granular casts suggests ATN.
Analgesic nephropathy (chronic interstitial nephropathy): Patient with chronic osteoarthritis treated with NSAIDs (and tylenol) who presents with signs of renal insufficiency (elevated creatinine and BUN) with mild proteinuria and sterile pyuria
submitted by โmedicalmike(82)
Analgesic nephropathy (2/2 ASA, ibuprofen) can present with AIN, renal papillary necrosis, and ATN due to vasoconstrictive effects. Intrarenal pattern of injury (BUN/Cr<20) with granular casts suggests ATN.