Glucose-dependent insulinotropic peptide (GIP) is secreted by K cells in the duodenum and jejunum, and it functions to decrease gastric acid production and stimulate insulin release from the pancreas.
Insulin promotes the peripheral tissue uptake of glucose and hepatic glucose storage, resulting in a decreased glucose concentration in the serum.
vs.
Motilin: is secreted by the small intestine and stimulates intestinal peristalsis. Motilin receptors are targeted by erythromycin and metoclopramide, used therapeutically in gastroparesis.
Secretin: secreted by duodenal S cells. Increases release of bicarb Rich pancreatic secretions and inhibits gastric acid.
Somatostatin: regulatory peptide secreted by D cells of the pancreas and gastrointestinal mucosa that inhibits gastric acid and pepsinogen secretion, gallbladder contraction, and insulin and glucagon release. Somatostatin would have an indirect effect on glucose through counterregulatory action of both insulin and glucagon.
submitted by โnamesthegame22(14)
Glucose-dependent insulinotropic peptide (GIP) is secreted by K cells in the duodenum and jejunum, and it functions to decrease gastric acid production and stimulate insulin release from the pancreas.
Insulin promotes the peripheral tissue uptake of glucose and hepatic glucose storage, resulting in a decreased glucose concentration in the serum.
vs.
Motilin: is secreted by the small intestine and stimulates intestinal peristalsis. Motilin receptors are targeted by erythromycin and metoclopramide, used therapeutically in gastroparesis.
Secretin: secreted by duodenal S cells. Increases release of bicarb Rich pancreatic secretions and inhibits gastric acid.
Somatostatin: regulatory peptide secreted by D cells of the pancreas and gastrointestinal mucosa that inhibits gastric acid and pepsinogen secretion, gallbladder contraction, and insulin and glucagon release. Somatostatin would have an indirect effect on glucose through counterregulatory action of both insulin and glucagon.