Child with atraumatic, progressive, bilateral knee pain with elevated ESR and otherwise normal exam/labs, most concerning for initial presentation of systemic juvenile idiopathic arthritis
Along with many other causes of autoimmune disease, SJIA is associated with anterior uveitis
Key idea: Classic NBME presentation is a patient with daily spiking fevers associated with a transient pink macular rash, along with signs of inflammation of labs (leukocytosis, anemia, thrombocytosis, increased ESR/CRP)
danielle359xActually this is oligoarticular juvenile idiopathic arthritis: involvement in <4 joints, usually weight-bearing joints esp. the knees; elevated ESR, usually ANA+, RF-; the oligoarticular subtype has the highest risk of all JIA for anterior uveitis.
No fever or rash=NOT systemic JIA subtype (not associated with uveitis)
RF- = NOT seropositive polyarticular JIA (associated with rheumatoid AKA subcutaneous nodules)
Not seronegative polyarticular JIA b/c involvement is with >5 joints, although this subtype is associated with anterior uveitis as well (but to a lesser degree than the oligoarticular subtype)+12
lilmonkeyGuys, you're so smart and beautiful. But I'm so dumb and ugly so I only remember the one classic NBME/USMLE association with juvenile arthritis - uveitis. And you know what - it works 9 times of 10.+7
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