Young patient with a father who developed a tic and committed suicide in middle-age who presents with progressive facial grimacing and signs of dementia, most consistent with Huntington disease (which is due to atrophy of the caudate nucleus)
Key idea: Huntington disease leads to triad of (1) Chorea (2) Dementia (3) Depression (and other psychosocial issues such as psychosis)
Atrophy of substantia nigra = Parkinsonโs disease
submitted by โstep_prep2(66)
https://step-prep.org/tutoring/