Remember: FAT RN

• F ever (T = 38.3C/101F)
• A nemia (hct=11%!!!)
• T hrombocytopenia (plt=52k/mm3)
• R enal involvement (Cr = 3.5 mg/dL)
• N eurological symptoms (fluctuating consciousness)

And the smear shows schistocytes, so you should be thinking MAHA

• Young pregnant woman presenting with fever, neurologic dysfunction, anemia with schistocytes (microangiopathic hemolytic anemia), and thrombocytopenia, associated with thrombotic thrombocytopenia purpura
• Mnemonic for components of thrombotic thrombocytopenic purpura or hemolytic-uremic syndrome: Brain FART –> Brain (neuro symptoms, more associated with TTP), Fever, Anemia (hemolytic), Renal problems (more associated with HUS), Thrombocytopenia
• Causes of micro/macroangiopathic hemolytic anemia (Anemia with schistocytes, unconjugated hyperbilirubinemia, etc.): DIC, TTP, HUS, SLE, HELLP syndrome, hypertensive emergency, aortic stenosis, prosthetic heart valves
• Henoch-Schonlein purpura: SAG –> Skin (palpable purpura), Arthralgias and GI symptoms (with association with intussusception)

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