NBME Step 2 CK Form 7 No cleaving of C-terminal peptides on angiotensin I (NBME Answers)

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Retired NBME Step 2 CK Form 7 Answers

step2ck_form7/Block 2/Question#10 (reveal difficulty score)
A 67-year-old man comes to the emergency ...
No cleaving of C-terminal peptides on angiotensin I 🔍 / 📺 / 🌳 / 📖
tags: pharm cardio

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submitted by ∗yotsubato(1208)

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Welcome back to Step 1 minutae... Useless crap they make us memorize, hell not even memorize.

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athleticmedic I had no idea what this question was trying to get at. It makes sense looking back now, but at the time I had no idea what they were talking about. +1

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submitted by ∗step_prep5(246)

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Angiotensinogen –(renin)–> Angiotensin 1 –(angiotensin-converting enzyme)–> Angiotensin 2 –> Vasoconstriction, increased aldosterone, increased ADH, increased sympathetic activity
Key idea: Although patient on ACE inhibitor will have decreased mineralocorticoid production in the adrenal cortex, the decreased angiotensin 2 will have a larger overall effect

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