NBME Step 2 CK Form 6 Carbamazepine therapy (NBME Answers)

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Retired NBME Step 2 CK Form 6 Answers

step2ck_form6/Block 3/Question#21 (reveal difficulty score)
A 47-year-old man comes to the physician ...
Carbamazepine therapy 🔍 / 📺 / 🌳 / 📖
tags: psych pharm

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submitted by ∗carolebaskin(109)

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Don't forget your sketchy!

carbamazapine is the anti-epileptic associated with blood dyscrasias, such as aplastic anemia and agranulocytosis

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tinylilron Isn't possible for folic acid deficiency and suppression of bone marrow by alcohol to be potential causes of the patient's decreased leukocyte count? +1

keyseph Folic acid deficiency would not explain the disproportionate decrease in neutrophils. Yes, this is leukopenia, but more specifically, this is agranulocytosis, which is a side effect of carbamazepine. +3

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submitted by ∗sassy_vulpix(23)

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Patient presents with agranulocytosis seen as a side effect of carbamazepine. Also scleral icterus, ascites & splenomegaly indicating liver toxicity.

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