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Retired NBME Step 2 CK Form 6 Answers

step2ck_form6/Block 2/Question#42 (reveal difficulty score)
An asymptomatic 32-year-old man comes for a ...
Selective IgA deficiency ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: Immuno

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submitted by โˆ—step_prep7(71)
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  • Selective IgA deficiency commonly leads to sinopulmonary and GI infections (especially Giardia) and pathognomonically anaphylaxis to blood products (because patient develops anti-IgA antibodies and reacts against IgA in blood products)
  • Key idea: Most common immunodeficiency and is most commonly asymptomatic
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submitted by โˆ—bigjimbo(67)
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IgA deficiency is in mind after reading anaphylactic shock on blood transfusion (residual IgA in blood product)

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