NBME Step 2 CK Form 6 Glucocorticoid-induced demargination and storage pool release of segmented neutrophils (NBME Answers)

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Retired NBME Step 2 CK Form 6 Answers

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submitted by ∗medicalmike(82)

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I think we've all been pimped on demargination reaction at some point...

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submitted by ∗step_prep7(71)

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Patient presented with a COPD exacerbation without overt infection (normal WBC with normal neutrophil count, afebrile) and then after receiving IV methylprednisolone (strong systemic steroid) developed a neutrophilic leukocytosis despite clinical improvements
Key idea: Two common causes of a neutrophilic leukocytosis are infection and systemic steroid use

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