Presentation most consistent with ankylosing spondylitis (young person with inflammatory back pain (stiff for >1 hour upon waking and improves with movement) who specifically has involvement of sacroiliac joints)
HLA-B27 positivity is a risk factor for PAIR diagnoses (Psoriatic arthritis, Ankylosing spondylitis, IBD related inflammatory arthritis and Reiter/Reactive arthritis)
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Dreams, sweet dreams...
submitted by โmedicalmike(82)
AS is strongly associated with HLA-B27 (however, not all patients with HLA-B27 serotype will develop AS)