Glucose transporter-4 (GLUT-4) is an insulin-dependent transporter, which is primarily located in adipose tissue and skeletal muscle. It does not play a role in the intestinal absorption of glucose or other monosaccharides.
GLUT-5 is an insulin-independent transporter that absorbs fructose from the intestinal lumen.
SGLT1 iscotransporter that absorbs galactose and glucose through the intestinal enterocytes
Reducing substances in urine= defined as unabsorbed di- or monosaccharides, are present in the stool.
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SGLT-1 is the cotransporter that absorbs galactose and glucose through the intestinal enterocytes. Deficiency of this enzyme manifests early in infancy as watery, acidic diarrhea and severe dehydration.
Fructose absorption is unaffected as this utilizes the GLUT-5 transporter instead.