The effect of fetal hemoglobin having a left shift on the O2-Hb curve is due to the fact that the fetal Hb has a greater affinity to the mother's oxygen and can leech it during gestation. It is similar to the effect of human placental lactogen (HPL), a hormone secreted by the placenta during pregnancy peaking at around 35-42 weeks. It stimulates insulin production but confers insulin resistance to the mother, thus shunting glucose to the baby. This can sometimes cause gestational diabetes if the mother cannot overcome insulin resistance. Both fetal Hb and HPL act to shunt resources to the baby, oxygen with fetal Hb, and glucose with HPL.
submitted by โshak360(23)
It can be re-accessed by making a purchase.
Purchase your membership here
$279$49dreIcesna tosnnnrcoaeict fo efalt lnhoboigem lretssu ni a eftl fiths of het xgyneo isiidcaootsn euvcr with eht nnmtieecnaa of the soiiglmda piocerotave idngibn trch.airacitssec
I kiel to mbeermer het !T,EA"DC nadts HIRG"T i:mmnenoc
sFtrcoa atht oevm hte engoyx issoantciodi ruevc ot hte htrig are heost ooigipyalchsl eastst reehw teisssu eden roem o.exngy oFr ,eaxmepl inugdr r,eescxie lssemuc ahev a ghrieh albtceomi ear,t dna unoltqnyeecs deen ermo nxey,go cderpuo ermo robcna dxdeiio adn atlcic cida, nad trihe mrpeatretue siesr omfr( kiWiidape on eth 2HO-b nciiodiassto ruvce).
$279$49