NBME Step 2 CK Form 7 Anaphylactic transfusion reaction (NBME Answers)

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Retired NBME Step 2 CK Form 7 Answers

step2ck_form7/Block 2/Question#32 (reveal difficulty score)
A 57-year-old woman with factor XI and IgA ...
Anaphylactic transfusion reaction 🔍 / 📺 / 🌳 / 📖
tags: Immuno

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submitted by ∗step_prep5(246)

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Key idea: IgA deficiency classically leads to Anaphylaxis to IgA-containing blood products + Atopy + Autoimmune disease + GI/sinopulmonary infections (IgA involved in mucosal immunity)
Anaphylactic transfusion reaction: Respiratory distress/wheezing, angioedema, hypotension, hives/urticaria
Urticarial transfusion reaction: Angioedema, wheezing

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sassy_vulpix Patient is a known case of IgA deficiency and we still gave them blood products with IgA? +4

adong clerical error clown face +

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submitted by embeemee(1)

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what is "allergic nonhemolytic transfusion reaction"? i thought it was the febrile one, but febrile is listed separately

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adong if this presentation were not as severe it would just be "allergic" as opposed to anaphylactic +

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