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NBME 23 Answers

nbme23/Block 3/Question#42 (14.8 difficulty score)
A 48-year-old woman has severe ...
Inhibition of gastric H+–K+ ATPaseπŸ”

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submitted by maxillarythirdmolar(35),
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Teh ontuesiq ssya etyh on'td rnsepsod ot inadctsa HTEN sska hcwih ouy to yednifit ihwhc durg si het tmos eeevctffi ta isgrspuspen acdi co,trpdioun NTO thwa the msot ectfeeifv dctiaan s.i Teh nserwa si .'sPIP

I illw ,say eevrh,wo I aws lkonogi rfo smgoihnte leki ieo.ortdtec

drdoom  lucid. nice catch. +1  
maddy1994  WHY not blockage of h2 receptors +3  
krewfoo99  @maddy1994. PPI are more effective than H2 blockers in suppression of gastric acid +1  

submitted by anechakfspb(27),

Why couldn't it be inhibition of gastric muscarinic (M1) receptors? Wouldn't that be the most effective overall?

submitted by yotsubato(968),
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Tihs attienp si usispoerevnn to naym n.ciatdisa yThe odtn fyiecsp ihcwh sno,e tub eth quontesi is scbllaiya ngsika hihcw taciaind is the grnt.steso tahT luwod eb sPP,I hhwic inbiiht agcirst H K asPTeA

yb_26  PPIs are not antacids! +3