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NBME 20 Answers

nbme20/Block 1/Question#31

A 66-year-old man has had fatigue, shortness of ...

Focal pulmonary fibrosis

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submitted by onyx(9),

A radiographically visible air-fluid level suggests a pretty large lesion (hence, “cavitary”). That's not going to become normal tissue again. Six months following resolution of symptoms you can expect healing in the form of a scar; that is, fibrosis but only in a single spot.

masonkingcobra  Robbin's: The basic mechanisms of fibrosis are the same as those of scar formation during tissue repair. However, tissue repair typically occurs after a short-lived injurious stimulus and follows an orderly sequence of steps, whereas fibrosis is induced by persistent injurious stimuli such as infections, immunologic reactions, and other types of tissue injury. The fibrosis seen in chronic diseases such as pulmonary fibrosis is often responsible for organ dysfunction and even organ failure. +