Normal hormone,normal male sperm study and normal menses: still can’t conceive then give TRY with clomiphene, that is Antagonist at GnRH receptor at Hypothalamas, Block Estrogen mediated inhibition of GnRH hence Increase release of GnRH>>>>>>inc. LH surge ovulation
Bromocriptine - would be helpful if the pt has infertility due to INCREASE PROLACTIN.
DES - is stopped in US due to clear cell carcinoma in young female born to mother.
Ethinyl estradiol - bind estrogen recepto>>>>>inhibit GnRH >>>>no LH surge: no use
(inc. Risk of endometrial carcinoma)
Medroxyprgestroene - is progestrin —-bind progesterone receptor....is(component of morning after pill)
researchers want to know CV risk about African American populations but do not have data for every person.If a researcher wanted to learn whether being certain ethnicity increase a risk of particular disease, it would not be practical to study every individual from that ethnicity . Instead, the researcher might select a sample of the population. A sample is a smaller group of members of a population selected to represent the population. In order to use statistics to learn things about the population, the sample must be random. A random sample is one in which every member of a population has an equal chance of being selected. The most commonly used sample is a simple random sample. It requires that every possible sample of the selected size has an equal chance of being used.
2,3-BPG created in RBCs during glycolysis. The production of 2,3-BPG is increased when oxygen availability is reduced, as occurs in chronic lung disease, HF& chronic exposure to high altitudes. Elevated levels of 2,3-BPG decrease Hb O2 affinity, allowing the release of more O2 in the peripheral tissue