NBME 24 Infiltration of lymphocytes and monocytes (NBME Answers)

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nbme24/Block 3/Question#43 (reveal difficulty score)
A 35-year-old woman with a long-standing ...
Infiltration of lymphocytes and monocytes 🔍 / 📺 / 🌳 / 📖
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submitted by ∗neonem(629)

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Histoplasma can act like TB and cause cavitary lesions and calcified nodules with fibrotic scarring. In general, fungi are combatted by lymphocytes and macrophages, not eosinophils or neutrophils.

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baja_blast Asthma history got me and I put Eosinophils.... but in hindsight I should have noticed that the biopsy is specifically of the nodules. RIP. +2

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submitted by ∗yex(128)

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This also refers to chronic inflammation & granuloma formation.

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submitted by dragon3(15)

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Can anyone explain why bacteria is neutrophils, viral/fungi are lymphocytes? I know this is a fundamental concept...

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lolmedlol i think neutrophils (in addition to lacking granzymes and perforins which are used to kill viruses and fungi) dont recognize intracellular things; viral antigens needs to be processed and presented on an MHC for the lymphocytes to recognize +7

usmile1 also neutrophils are only seen in acute inflammation. This pt has longstanding inflammation which is associated with monocytes, lymphocytes, macrophages, plasma cells. +4

usmlecrasherss Neutrophil come and goes quick like day or two , after that rest of immune cells take care +

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submitted by ∗sexymexican888(46)

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HONESTLY WTF IS THIS QUESTION WHY TF DO THEY SAY ON CORTICOSTEROIDS that shit fucking confused me... ugh frustrating

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suey Steroids would cause increased neutrophils but not necessarily an infiltrate, and they would not be attached to lung tissue +

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