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NBME 24 Answers

nbme24/Block 1/Question#41 (reveal difficulty score)
A 32-year-old woman who is 20 weeks' pregnant ...
Misoprostol ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +6  upvote downvote
submitted by โˆ—m-ice(370)
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Misoprostol is a prostaglandin analog (PGE2) that acts on the stomach to promote mucus protection of the stomach lining, but also acts in the uterus to encourage contraction, which makes it useful for abortion.

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usmile1  perfect except it is a PGE1 analog, not 2 +6
krewfoo99  PGE2 will increase uterine tone (Pg. 270 FA 2018) +1
drmohandes  Misoprostol prevents NSAID-induced peptic ulcers. Side-effect: also gets rid of baby. +3



 +2  upvote downvote
submitted by โˆ—madojo(212)
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Going through other answer choices:

Bismuth and Sucralfate is used for ulcer healing or travelers diarrhea, it provides physical protection by binding to the ucler base and allows bicarb secretion to establish pH gradient in mucous layer.

FamotiDINE is a H2 receptor blocker

Omeprazole is a PPI and increases risk of C diff infxn, and decreases Mg and Ca absorption (can cause fx in elderly)

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