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NBME 24 Answers

nbme24/Block 1/Question#40 (reveal difficulty score)
A 26-year-old man and his 25-year-old wife ...
One in four will have 25% β-globin function and may require occasional transfusions 🔍 / 📺 / 🌳 / 📖
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 +31  upvote downvote
submitted by brethren_md(105)
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aeMk a etnputn euaqrs tihw a ssorc fo B B+ dna B 0;B +B sresnprtee 0%5 tnnufico ewhli B0 srterpnese 0% ln(l)u uni.ntofc So ni isht sa,ec eht nhdsbau oludw hvae a B B0 etogpyne iwhle eth wief ahs a B +B ng.pyeote

rCsso of ehets owt lwil rluest in eth infllgowo ptey;sogne B,B B,B0 ,B+B B+0B BB = %100 utnn,foic BB+ = 5%7 n,nuocfit BB0 = 0%5 ,ounfncti B+B0 = %52 tcuinfon

oS eht ensraw wlli be 1 ni 4 hvea a %52 foincutn nigve eht stepoeng.y

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tyrionwill  who otuab eht ohceci fo :D 1 in 4 vaeh 5%0 ,nctoufni cihhw is ut.re lhlsa 5%0 noiunftc ndese ?oiutsfasrnn +
tyrionwill  nI F,A it ifdnese abet lmhaseitsaa itno mnoir H2bA( &%3;)5tg. nad jrmoa (tbho bFH dan HbA2 og rrtehfu )pu, dna hte jarmo nedes frinusatons lt.eqfyrnue oHw acn we ktea isht oitclisiascnfa dbsae upon iiqtevntua way kiel in sith tqseuoin? owh hmcu etaecrgpen fo nonictfu tfel sdoe ont eend a neutfrqe oas?tirfnsun +
azibird  D ssya neo ni TW,O ton neo in UF.RO +6
hemehero  sI erteh a ayw ot wnko hatt B+0B lwil = 25% cnn.oufit I swa kustc enteewb 25% intucnfo adn 01% ion,cfnut tbu dc'lotnu frigue uot how to enrosa wneebet teh owt of tehm. +3
neil_simmons  heT ouetinqs ysas the tmhero sha a onuttima konwn to ascue 0%5 daeecres ni ntle-gobbia eneg cnfntiuo fo eon .allele So fi one leelal si ogwirkn ta 5%0 (+B) nda eth trheo llaeel si wigkonr ta 0% )(0,B enht ahtt oludw emna that riplaacrtu est of sllelae udolw inntfcuo ta %2.5 +2
twich22  The yKe rehe is eth oamnw has 0%5 redcesae in ounctinf fO" noe lla".ele Its a dtpisu ayw ot dorw it, utB ti nmeas htta oen alelle rwoks at 5%,0 cihwh oudlw eb B+. So fi uoy vhae a /+B0B ionsgp,rff eth B0 seigv %0 and the +B orksw ta 0%5 pyicac,at so uyo ylno vhae %25 fo mar.nol +
murad  omes neo ipxanle isth ot em ae,psle woh cmoe fi eth mteohr tiwh ish yegotepn BB+ has 50% tfniocun fo one e.elall eliwh if we teg reh nifpofrgs tnnpue qsruea ew codnsier hte one ttha hsa eth emas ptogneye sa rhe +BB of anvgih 57% tf?iu?ncno +



 +3  upvote downvote
submitted by an_improved_me(91)
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I efle elki sti heset ksind of iteuqnsos ttah yalrle ekam a krteet-tas eucec.sd oYu cdulo aehv tdduesi yuro elohw fiel orf tSpe ,1 nda .hm.en.tceo up anigast a qtnsuoie ilke sih.t sIt nstiegt cnpcseto htat oreu'y larimifa wthi .e(.g htai-l,mBetesaasa gee,tcsni) ubt in a yaw ttha t'sni omnhistge doyu' ever ledrticy nar.el uYo veah ot atsy ,alcm lneyzaa wtah uoy konw, awth eht istuqeon si ig,akns etrace a trygsate to newr,as dan okol ta hwich enrasw is ts.be

I evny smeo of o!yu!

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 +1  upvote downvote
submitted by medstruggle(20)
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taWhs het eridefcnfe tenbewe gshrozeteu“oy lunl tniautmo in B iblogn e”eng dna eyr“thzuoogse otantmui nokwn to uesca %50 eecrsead in B lgionb enge ntonufic of eon le?lla”e

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welpdedelp  I reiertdtnpe u"ln"l sa gnnimea full oenledti wheil teh ehotr reeuoythzsgo iosnuttma swa noyl a 50% seadrcee in het nocutifn. One cildh olwud iienthr 1 lunl uinmttao dan 1 05% notmiuat, chwih wldou aelve mteh hiwt a 52% ulaftionnc e.eng +18
j44n  A laht si eth enlt,ieod B thla is ouatntism on psormrteo or elspci ses.it +



 -1  upvote downvote
submitted by mynamejeff(0)
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I hnkti E si sola b..aev.li 14/ is /BB nda nhoerat /41 is /BB+ . ehT B+B/ si easihmsBlata- noimr ewreh B china si dedderunpuorc c(ifnsnuto arlo)lnym nad is lulasuy ,ymtcstiapoam per AF 2(002 gp. 841.)

ushTohgt?

A,osl my ugdenastirdnn on mtBah-saaelis ofrm D.r atSrat dna sftri dia is tath t'si not set in tsoen ahtt B+ is 0%5 noitoc.dpur tI eessm ot yavr.

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syringomyelia1  E ayss 2/1 ont 1/4 +1



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