avocadotoastPlease no one give a poor girl with a yeast infection amphoterrible+3
fatboyslim@alexxxx30 according to FA2020 page 153 Nystatin is only for oral. In the 2018 FA it did say it can be used for esophageal but they edited that in 2020.+
isn't candida yeast form under body temperature? why the picture shows a mold form?
danielautranMaybe because the picture wasn't taken from inside the body+1
fatboyslimMost dimorphic fungi are "mold in the cold" and "yeast in the beast". Candida however is budding yeasts w/ pseudohyphae in the cold, and germ tubes inside the body. The picture in the question is showing budding yeasts with pseudohyphae :)+1
submitted by โyotsubato(1208)
So for Candida we can use
Azoles (fluconazole) (inhibit CYP450 demethylation)
Amphotercin B (pore formation in fungal cell membrane)
Caspofungin (prevent crosslinking of beta glucans in cell wall)
or Nysatin for oral or esophageal cases (pore formation)
This question is saying that she is taking an ORAL drug to treat candida vaginitis.
Amphotercin is IV
Caspofungin is also IV
so we're left with azoles
Azoles inhibit synthesis of ergosterol by inhibiting CYP 450 that converts lanosterol to ergosterol.