NBME 22 Carboxylation of precursor proteins (NBME Answers)

NBME 22 Answers

nbme22/Block 3/Question#12 (reveal difficulty score)
An 82-year-old woman has been bedridden since ...
Carboxylation of precursor proteins 🔍 / 📺 / 🌳 / 📖
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+6 upvote downvote
submitted by ∗humble_station(85)

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nafWriar biihtsin tiV K epnedndte tnyhssesi fo rcosfta ;pma& oerpni.st

Vti K is eynracsse orf teh tiomnatuar fo goclnitt scfator I,I II,V XI, X nad penitro C &p;ma S

So a drgu thta anc itibnih eth lrtioyxoacabn of spcrorure oerntisp ro in ohrte rwdso iibntih the turonaamit fo eht lntotcgi osacrft ilwl esdecrae teh ksri of btmiroshso in iths eitnatp.

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Extra note: Thrombomodulin alpha (a recombinant drug) can increase thrombin degradation and Protein C activation, hence can also be used for anticoagulation. (But this question asked about decrease in which of the following)

+3/- apurva(101)

+2 upvote downvote
submitted by ∗haliburton(225)

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awnrifra hitiibsn hte hstnysise fo csarfto II, I,IV XI, ,X ,C and S by loibkncg ciruoetnd of dozixdei miaitvn .K eTh eenmzy Eopedxi setuRdcea si iitednhbi yb nriwa.fra hTe uedcerd aie(v)ct ormf of it.v K is a afocrcto ofr tamlgm-aglmayu lye.xobsarca

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link981 So crtaosf I,I ,IVI I,X dna X rea purcoersr rsoeinp?t TFOG +2

+0 upvote downvote
submitted by ∗humble_station(85)

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rWnfiara bhsniiti iVt K eeepdnndt ntsisyehs fo rfctsao p;am& nrst.epoi

tiV K si rcyesesna orf the oatmrianut of ictgtnol rcotsfa II, II,V I,X X adn poetrin C p&am; S

So a grdu ttha nac inithib teh aoitxaylbcnor of uprscerro nrteospi or in trohe wdosr ntibiih het aarmnitout of het nctlitgo oaftrcs wlil eecdares teh ksir fo irssbhootm ni hist ap.tnite

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ajss hits si hyw rnawrfai is venig sa ohirxsalypp etarf tsih tpey fo ersgeusir +

-2 upvote downvote
submitted by ∗sup(31)

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hWy nto GP2I yb ayw of AS?A pcllEiyeas ginve trheo rnaswe cociesh fo sroenipt C + :S os'tned wafrnria laso psressup ehset?

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imnotarobotbut tPerino C adn S ear -,cotmhtiTNAbrIo so ghouhlta rainafrW sdoe eeardces e,tmh ythe tnud'owl scerdeea hte 'nstepati rski for ossmhbroit +1

epr94 the touqiens ksa espo"uisnprs" fo icwhh eon llwi eecdsaer kisr of rssmbtooih fi oyu persssup C nda S chiwh adn htbnmiotra-oitc yuo egt bmctohitor +3

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