ohSrt :naresw All egnse era eerspnt in thob B adn T cllse, ubt tehy rregeraan dna xssrpee peestrcor thta ear ifscpeic to rieht leeangi. ehirT era nedpdntneie JVD geionsr rfo B cell peoercrt igonaetner dan T clle perercto !rtenaneiog hiTs kiwi tcilaer hssed thgil on :iths
_e_#er:einal_.nio/mltrsenbpTeciJr/tkVoDi/tk(ewprhosiocpwa)dcig/i.t
I oto tcylrlaiga ssdemi .h.tsi tbu it si lyaualtc os elpims hatt ew rea nsgmiis eht stoerf rgothuh teh ester -hlW e-i htbo B and T eclls drgnueo VJD arrnreg,etnmae het ,V ,D dan J esgne era IEFRTDEFN EGSNE pdtiees ebgni aedozrgni nad hteoferre sfdciaseli ni a rliimas hfnaiso deu ot hiret hraeds ndee ot etnragee vireesd cr.urtssetu To ekma seattmr rmoe cifosung,n hotb sest fo VDJ esgne rea no chmmreooso 4.1
iTsh is hyw the MEBN ipeecsdfi htta eyht rea gaintgg THE SMEA J IEONRG whcih si ahtt of eht B lcel eprtcero egne J e,ngrio tno teh T elcl erecptor egen a-tbeJ ieorng ese( wkii .traec)il hTe B lcle eoptrcer enge is otn rdargeaern in a T ,cell if it wsa, T elslc lwduo hvea t!oaedisibn
hTe ayw I hotghut atuob stih soiuentq was atht in MM rheet si a NOT fo anotbisedi ebing mad,e so hte DJV engemts is gineb brkeno dscderpeltrueern/gaae/ yman etism nad sah nebe osehnedrt ot .51.kb sA rfo teh T ,lesCl hatt gornei i’tsn being udes (nscie erhte si on naollc ospineanx or l)eonsicte so tis’ siltl got teh lulf b6k lntegh ehcon.uutd
Wihle T leslc do use eht JDV eiorob,icnatnm hte T lelc oecetprr sncaih rae tefifednr gnese romf the B s'lecl yavhe and glthi .cahnis icneS ethy sdeu a B llec Jeirng-o peb,ro het T c'ells abdn wlil eb uchm larrge sa hsit raea fo ist AND t(eh B cell yheva or itghl cihan n)eesg heav otn eben rrndeaeagr -- iadnest tsi T cell erteprco segne eahv eebn na.rgeedarr
es/pehz_rixspethonb.e/owp4ranc2ertsbitup_tcoe17.lqn_sw/weonesonai/bmmtt/e_dr/t/mdeitm/:qln2p__slu
submitted by ∗sacredazn(101)
It can be re-accessed by making a purchase.
Purchase your membership here
$279$49 65% OFFehT cenpoct is a cvlotnueod yaw of ngikas if yuo nwke hwo JVD enmotbrcioain k,srow hwich si ttha ti is ltucylaa an alexpme of lrianget teh DNA fo eht BT/ cmtoeyyl.ph
reSutnho lotb nuetehq:ci oS nwhe tyhe ues a poreb atsinga oems oine,rg adn otgttuiupn a ezis of 1.5 kb ro 6 ,bk stih is telling yuo eht esiz of teh DAN emrtngfa ni aehc lecl dnetos’( eattmr fi eyht asy J oeprb or nctsoant rognie ,pboer thye’re jtsu niagys yee’rth rntageigt mseo diceluetno eenucsqe dnfuo in eht gI scu/ClToR bate icahn locsu epvsriytcele fro TB/ .c)ells
I tikhn hte fgocunsin trap udclo eb eidnogwnr ohw you nkwo ehwerth r’yuoe altpyr hgrtouh annregaermtre we(rsna cehsioc B thru )D ro if it hnta’s ccorrude ta all yet cc(orrte w)rsena. H,ree hte tpocnce si ttha B sllec ugerodn (DV)J egternrmeanar in the noeb owmrr,a ewihl T sclel do ti in het m,thysu nda ti all sphnaep ta oe.nc So a aapslm clel in teh lobdo liek in Muptelli Mylemoa udolw aveh ulfly rneugnoed etnobrmi,ioacn ehilw a T clle ni teh loobd lduoc terehi eb ullfy teacudde dn(a heva sfnihdei JVD maeirnobco)tin or mmuateri ’h(tsna aettrds DJ.V)
nciSe the T elcl eegn saw 6 kb nda ftendiiyel eiggbr anth eth 51. bk gne,e eth T llec a’hnts onneudger ntrcoionembia .ety
$279$49 65% OFF