According to UW, contact dermatitis can be CD4+ and/or CD8+ T cell mediated, with urushiol (poison ivy) dermatitis being primarily mediated by CD8+ T cells.
would anyone be able to clarify what the others would be? A) Allergen mediated vasoconstriction, leading to ischemic tissue injury: Type I B) Binding of antigen to IgE on the surface of mast cells leading to mast cell degranulation: Type I C) deposition of antigen-antibody complexes within postcapillary venules, leading to activation of complement: Not sure D) Phagocytosis of antigen by neutrophils, leading to oxidant mediated tissue damage: Type III?
submitted by โmcl(670)
Poison ivy triggers a type IV hypersensitivity (mediated by T cells); only one of the answer choices mentions T cells.