eTh enLriaevwe Burk tlPo is ayniml tereierptdn yb tsi X dna Y .tcehstiT eeprn nuitqose stetas taht ggivin 6B eeanrscis teh itatiycv to omarln selve,l iwhch amnse eth tcviayti dulsoh be eht smea as the m,lcoHenan. re tihre Y prtneitec odlsuh be teh meas, so we rae enbtwee schecio B dan .C A nda D do otn aveh the smae Y icperentt as gaihnl er.Hrom onnccnetotsair fo B6 cudesa ticityva ot ocmeeb norm,al dna so mxVa iwll tno be gicnghna nda ew acn calcne A nad . DA sah a woelr axVm adn D hsa a mchu iehgrh VeT .hmxa eerffednic eewnbet B dna C is in rtihe m.K vMinog ot eht elft on eht X isxa mkase the Km weolr dan ellst uoy atth tyifnaif si irghheso uoy lodwu nto dnee more 6B. Btu in our eacs iitfyfan of teh znyeme for 6B si raelly lw,o ihchw si wyh ew ened a ton ermo 6.B
nI rsua,mym we ntaw hte smae mVax nda a hriegh eK .Wm awnt the "lomrn"a iatyvitc esm(a axmv as nalrom) dna ew ende hrhegi umtosan of 6B ofr ssuescc t ifyofains of the yznmee rfo B6 is raolpbby yerv .wol
ceiCho B sha a )-1(/mK vealu corlse to 0 hwhci mesna mK is lwoer nda ifafyitn of the nzemey rfo sit srasettbu si uersp wlhso T.i emksa neess as gvingi hhgrei unstmoa fo the ee"mpvco"titi srteutasb 6B si n.ephigl
eNinged hgih"re rnten"iccnstooa of teh 6B rfo nmzeey ttcaiiyv si athrone yaw of agiyns Km si ihehrg ncesi erom si eieurqrd ofr 21/ xamv c.ityviat nearIsced Km valeus utsrle in /1Km bngie lsemrla rl(oces ot 0 no the i)-s,xax hhciw is omenesatdrtd in ranwse cceiho .B
A alonrm"" yemnze vttcaiiy ni hte cseprene of hgierh 6B cecisantnorotn semna ttha maVx si tno ichggnan, utb Km is.
Soem of seeht xnnioaspltea raelyl nigdo hte .msot If eht eeynmz is leba ot aeicesrn to mrlona ytiacvti hwit a ehghir lvele of the bsstu,erta ttah senam r’eew in a victieemtop itirinhbo tinutos.ia Cemteioitvp wyaasl cssreos on hte apgr,h os we anc ilaimente A dan D.
oNw we zaayenl m.K eW nawt lmlas sK’m rof tpnoet nesemzy. ezSi oesd ont alwysa rtamet 😉. eEcpxt in shti acse we dno’t wnta htta nyeto,cp we nwta to olko fro a al/e(lry1 ibg ,)Km vale(u atht is ocrsel ot r),eoz cb ew atnw a wkae ibg mK ot be aleb to wpevorreo hte vimetpitcoe iirtbhni.o igoaCmrpn teh rmginneai 2 hio,cces B ash a mK aleuv eolcrs ot rezo os ert’hes yuor e.warsn
Fro htis oiqtn,use I wsa gtknnhii atth tyeh sadek uoy remcpoa ot a “oln”mar r,esnpo so hte maVx ldow’unt hngcae since etyh etsat tath his yttvaici nurestr to a lomarn ev.lel nOyl eht xxis-a lwuod eisnc ti dlwuo eb at inrcdeesa itnnrooccsetan in o.oirmnpsac
oS i dnofu tsih oquitnse i.souicrl..ud het ptxlnoieanas vdoidrep idd nto relayl eaclr it pu for e,m but i htnik i senduatdnr ti wno pslae(e rerccot em if im' .wn)ogr
tisrF nad roo,etsmf mI' not vnee usre fi tsih si rltuy a uvik-reanlebweer ,ptol icnes het siXax- is otn .mK1/
uB,t emor lleyg,rena I itrde ot uddratnsne twha adepepnh at tohb tmeseexr of P]P[L adn ctoliV.ey
P :skAPL uy:foslre whree no the hrpag si PL][P gsei?hht ell,W fi het xisa-X si uelaq ot P/,1PL LPP luwdo eb ta its ehtgsih ta het evlua tseclso ot 0 on teh i.axxs- k(hitn: ahtw si 1 vdedidi by a ionbil?l EYRV CSOEL OT Z.)REO This oudwl ocdnesrpro ot a pnoti anlgo teh sx-aiy fro eth ysnemze vytiati.c In teorh wd,sor PPL si ta sit htheigs ctrocotainenn ta hte asrhpg tptrYe.iecn-
mbemerRe tahw we aslo a:dsi enhw het matdute ynemze si durano slto of ,LPP it lcbylsiaa cfutisnno ikle a lmn .zeenym iTsh s,emna ttah hte xVam fo eth meattdu mzeyne si nauvieqlte to hte axmV of hte lnoamr men.yez efeo,rrTeh The mV1x/a of obht zsemeny rea nqtei.ua.e.lv at teh !Tychr titine-eps si gi!b fI oyu etg this ,fra tenh uoy nca maeeiintl A)( dna ),(D ncesi teehs rsahpg have itdnreffe nc-sYtetepri (nfdteerif sx)em-Va ofr htrei stirvpeeec smyezne.
vnMgio n..o.
ceyVitol V(:) heWn V is at its sighthe (.ei. x,amV) hte value of 1V/ uwold eb ta tis swtel.o agA(in: thikn fo it ayrcaipl:lct hwat is 1 ddeivid by 1 ?ionlibl ~)0! eorr,fThee hte eaulv of 1V/ si ta sit solwet when the xas-yi is uelqa ot .0 e,eefrrTho ehT Vxma of shit ursocc hewn teh yax-is is ecosl ot zr...eo sHree teh ignht ..toh eesht emzesny iqueerr eiftefndr leelvs of LPP ot ereatpo ta axm.-V ee,reRbmm the xVma- fo eth DTUTEAM zenmey iwll neaphp at a chum HHRIEG P.L[P] rO norcyve,esl the -mVxa of teh ARMOLN eezmny lwil phnape ta a chmu EROWL PL..]P[.
be arewa hatt teh x-isxa orf stih iutneqso is not K"m" Bi(vt6 si nto hte etart'suhbtast [6ti/1.]VB ot ifip,sym sebaecu hte Vmxa si ganno tysa teh as,me uoy tusj dnee to cnseirea B6]vt[i ot etg eht smea aVxm aka( tfhis ot gtrhi on het x.xs)ai- noD't be odfeol duaron by eht nsiqoeut treir.w
yoNdob sah ednrwesa isht seinoqtu rhgothu teh esln fo a rlgennai ebejcvtoi quite tye os h'seer ym 2 enc:ts mK si ECNRAIDSE cb shti neaiptt sah na ynzmee hwit na ealvrlo EROWL tiifyanf (nca eb ccretodre ot arnmlo erfta an irnesace ni tst)aesubr hhciw si ttccrriihaaesc fo ITCEETMIPOV iobnihitn,i cwhhi is wyh eht ieln of eht pt. si neo of piitecetmov hitiobniin no a BL oltp
ehT isneutoq si yblsacila igsntet up a stoitniau lrmsiai to thta fo a mctoievtepi bir.thonii Tehy ysa hatt hhireg rinctstoaconne of pxirdalyo hpeopasth sesnaeric eht tavicyit fo hte nmeezy to mnaolr esllv.e ilyamlSir, ewnh you hvae a moitetcvipe tiboniihr nad rsceeani eth aoctrnnocinet of rssae,uttb teh mzyeen anc hvaeeci teh saem xVam as fi uowhtti teh .bitrhnoii
emebRrme )1 motctieipev ionshiibrt ~ nsile ssoCr ta eci-)yn rt2est cvione-miNoettp ohibrsiitn ~ on lein sscro
Long wrsnea ae,dah tub bera ihtw e.m
T:IHN v slook kdin of eilk ,y ewahres k ksool eorm keli x.
n-ptctieyer = /Vmx1a
tnixret-pce = /mK1
otNe thta Vmxa, as a semurea fo caem,nfpeorr anc be dlreaet ohtguhr mnay sh.nitg enMhweail, Km is a ste rtciaactehiscr of teh zyen,em and tancon eb erdt.lea
nI isht l,xaeepm eht emeyzn poemearncfr )xmaV( is endarcise by anrgceiisn the ntiaimv arocftoc os htat it rcsheea a omrln""a aitviy.ct oeweH,rv the enymze is llist ntrelhiyen itysth deu ot a gleictnnao tdefe,c so the Km ytass eht a.mes
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