This is a pretty good figure showing the conversion of membrane phospholipids to arachidonic acid/leukotrienes etc.
Blockade of COX enzyme by ibuprofen results in decreased production of prostaglandins H2 and E2, while causing the precursors to "back up" (increased arachidonic acid). This, in turn, results in increased production of leukotrienes.
submitted by โmcl(670)
This is a pretty good figure showing the conversion of membrane phospholipids to arachidonic acid/leukotrienes etc.
Blockade of COX enzyme by ibuprofen results in decreased production of prostaglandins H2 and E2, while causing the precursors to "back up" (increased arachidonic acid). This, in turn, results in increased production of leukotrienes.