NBME 20 Doxycycline (NBME Answers)

NBME 20 Answers

nbme20/Block 4/Question#29 (reveal difficulty score)
A 15-year-old girl is brought to the ...
Doxycycline 🔍 / 📺 / 🌳 / 📖
tags:

+8 upvote downvote
submitted by ∗breis(56)

get full access to all content ⋅ pick a username

Doxycycline is a Tetracycline (binds 30s subunit) and is used off label for treatment of Acne. Can cause discoloration of teeth, and is known to be PHOTOSENSITIVE.

This patient had diffuse erythema and mild edema over her face and extremities, most likely from sun exposure while being on the med for Acne.

FA 2019: pg 192

get full access to all content ⋅ pick a username

Tetracyclines most common adverse effects are nausea/vomit/diarrhea and photosensitivity. Can affect bones and teeth of newborn if given to pregnant women. Also this drug class covers GAS, GBS, +/- MRSA, respiratory flora and intracellular.

Why Cipro is not the answer: Macrolide covers GNR + Pseudo, therefore not a treatment for acne (skin flora). And common adverse effects are C.Diff infection, QT prolongation, tendon rupture, teratogenic effects.

+4/- lilyo(94)

+1 upvote downvote
submitted by ∗hayayah(1212)

get full access to all content ⋅ pick a username

An adverse effect of doxycycline is photosensitivity.

get full access to all content ⋅ pick a username

rio19111 Why not Cipro? +1

raspushok Which antibiotics increase photosensitivity? Several antibiotic classes commonly cause photosensitivity, including tetracyclines (doxycycline), quinolones (ciprofloxacin, norfloxacin), and sulphonamides (trimethoprim/sulfamethoxazole, sulfasalazine). The tetracycline minocycline is not generally associated with photosensitivity. WHY not damn cipro? +

medninja I think it is because Cipro is not commonly used for acne treatment +4

+0 upvote downvote
submitted by ∗lilyo(94)

get full access to all content ⋅ pick a username

-1 upvote downvote
submitted by ∗drdoom(1206)

get full access to all content ⋅ pick a username

[deleted]

get full access to all content ⋅ pick a username

Must-See Comments from nbme20

amorah on Cytomegalovirus infection
masonkingcobra on Contact with parakeets
hayayah on Capillary hydrostatic: increased; ...
hayayah on X chromosome-linked isoenzymes
medbitch94 on Mannose 6-phosphate
hello on Capillary hydrostatic: increased; ...
hayayah on Osteoblasts
imgdoc on Hypophosphatemia
hayayah on Missense
celeste on 50%
justgettinby on Omeprazole
andrewk1 on Cold, dry air
yotsubato on Jugular venous pressure of 12 mm Hg
strugglebus on Drug effect