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NBME 16 Answers

nbme16/Block 1/Question#21 (reveal difficulty score)
A 50-year-old man comes to the physician ...
Collagen ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +7  upvote downvote
submitted by โˆ—notyasupreme(48)
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Just wondering if someone could explain the difference between collagen and elastin for this one? I thought either or could be used for tensile strength. Anyone have clarification, don't know why collagen is the best answer!

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notyasupreme  Lol, never mind I realize, it's a scar and that's type III collagen! +6
meryen13  type III is whats usually present but then it gets replaced by collagen I in the scar tissue to add more strength. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352699/ +1
i_hate_it_here  It is also the disulfide bonds that add to tensile strength of collagen, while the inter-chain fibril cross-linking that leads to elastins elasticity FA2020 pg: 51&52 +
xw1984  I think the Q emphasized postoperatiive. Maybe the production of elastin does not increase much comparing to collagen. +
topgunber  i think they would refer to elastin in cases of arteriolar compliance +



 +0  upvote downvote
submitted by โˆ—dentist(94)
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this question is a fancy way of asking about wound healing. phase 1) cleaning, 2) organize, 3) strengthen. FA2020 p.216

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