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 +0  (nbme20#37)

I don't get this. Shouldn't the kidneys start correcting the bicarb levels afer 5 days? The delayed phase of the correction since they take time... and in the question they're asking "now". We have metabolic alkalosis since HCL is lost, so the body will try to correct it first by hyperventilation and later by increased excretion of bicarb. Bicarb should be low... (unless I'm missing something due to being exhausted)

thefoggymist  Nevermind, I think I got it. Beta intercalated cells cannot function and excrete bicarb because we don't have chloride. Yea apparently I was exhausted.




Subcomments ...

submitted by hayayah(411),

Missense mutations involve a nucleotide substitution resulting in changed amino acids. Sometimes the effects of missense mutations may be only apparent under certain environmental conditions; such missense mutations are called conditional mutations. Many missense mutations result in proteins that are still functional, at least to some degree.

Also, all the other answers would probably leave you with either a greatly altered or non-functional protein.

thefoggymist  I chose nonsense because I thought it'll make the enzyme shorter (since less bonds = more heat liable = can't work at 42 degrees) but yea, probably won't work even at 30 if it's an early nonsense. +1  


submitted by hayayah(411),

Little finger = ulnar nerve.

C8-T1 are the roots of the ulnar nerve, which is a branch of the medial cord. The ulnar nerve is not found in the carpal tunnel (the medial nerve is).

Ulnar n. damage can lead to loss of wrist flexion and adduction, flexion of medial fingers, abduction and adduction of fingers (interossei), actions of medial 2 lumbrical muscles. Loss of sensation over medial 1 1/2 fingers, including hypothenar eminence.

sugaplum  Also to add: since it is a bilateral sx it is more likely to be coming from the spinal cord then from equal compression of ulnar nerve (in guyons canal) on both sides. unless she is a cyclist +1  
thefoggymist  shouldn't the other nerves of the same roots be affected? +  
thefoggymist  shouldn't the other nerves of the same roots be affected? +  
charcot_bouchard  Not really. In klumpeke paralysis ulnar nerve s/s dominates (Almost same cause) +  


submitted by hayayah(411),

Little finger = ulnar nerve.

C8-T1 are the roots of the ulnar nerve, which is a branch of the medial cord. The ulnar nerve is not found in the carpal tunnel (the medial nerve is).

Ulnar n. damage can lead to loss of wrist flexion and adduction, flexion of medial fingers, abduction and adduction of fingers (interossei), actions of medial 2 lumbrical muscles. Loss of sensation over medial 1 1/2 fingers, including hypothenar eminence.

sugaplum  Also to add: since it is a bilateral sx it is more likely to be coming from the spinal cord then from equal compression of ulnar nerve (in guyons canal) on both sides. unless she is a cyclist +1  
thefoggymist  shouldn't the other nerves of the same roots be affected? +  
thefoggymist  shouldn't the other nerves of the same roots be affected? +  
charcot_bouchard  Not really. In klumpeke paralysis ulnar nerve s/s dominates (Almost same cause) +  


I don't get this. Shouldn't the kidneys start correcting the bicarb levels afer 5 days? The delayed phase of the correction since they take time... and in the question they're asking "now". We have metabolic alkalosis since HCL is lost, so the body will try to correct it first by hyperventilation and later by increased excretion of bicarb. Bicarb should be low... (unless I'm missing something due to being exhausted)

thefoggymist  Nevermind, I think I got it. Beta intercalated cells cannot function and excrete bicarb because we don't have chloride. Yea apparently I was exhausted. +