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Comments ...

 +0  (nbme20#20)

Diagnosis: Pneumomediastinum (FA 2019, 659)

+Hamman Sign=Crepitus on cardiac auscultation

Etiology: spontaneous (due to rupture of pulmonary bleb) or 2° (eg, trauma, iatrogenic, Boerhaave syndrome).

md_caffeiner  also look on FA 667 traumatic pnx where it says "rib fracture"

 +0  (nbme20#7)

its primary hyperparathyroidism caused by parathyroid adenoma. addition of the peptic ulcer suggest Zollinger ---> MEN1

but none of that is imp because that's not what they are asking. All they are asking for is the function of PTH.

rio19111  Stones, groans, thrones, psychiatric overtones ---> symptoms

 +1  (nbme20#30)

I think a lot of you missed the point. The answer is Cortisol because it helps maintain blood pressure even in the setting where he is malnourished.

rio19111  FA 2019, Pg. 329
pakimd  according to pathoma, cortisol is the hormone neccessary for life. in a condition like the one presented in the Q-stem the most important hormone will be cortisol.




Subcomments ...

submitted by rio19111(5),

its primary hyperparathyroidism caused by parathyroid adenoma. addition of the peptic ulcer suggest Zollinger ---> MEN1

but none of that is imp because that's not what they are asking. All they are asking for is the function of PTH.

rio19111  Stones, groans, thrones, psychiatric overtones ---> symptoms +  


submitted by killme(3),

The concept being tested is "what does PTH do that leads to hypercalcemia" https://i.ibb.co/sKPdVj3/image.png

yotsubato  ugh, bullshit. I was trying to figure out an actual disease process here. +1  
rio19111  its primary hyperparathyroidism caused by parathyroid adenoma. addition of the peptic ulcer suggest Zollinger ---> MEN1 but none of that is imp because that's not what they are asking. All they are asking for is the function of PTH. +1  


submitted by ergogenic22(46),

aging results in increased arterial stiffness (change in Extra Ccellular Mmatrix composition - decreased elastin, increased collagen deposition); ISH is responsible for 60-80% of HTN cases in patients > 60. Also, decreased compliance as a result of aging causes increased pulse pressure

rio19111  why not dev. of coronary atherosclerosis? +  
pakimd  @rio19111 i think the Q stem is asking in absence of any lesions of blood vessels; the number and severity of which increase with age. So with normal aging SBP should increase in isolation which may then result in the development of coronary atherosclerosis- if that makes sense +  


submitted by rio19111(5),

I think a lot of you missed the point. The answer is Cortisol because it helps maintain blood pressure even in the setting where he is malnourished.

rio19111  FA 2019, Pg. 329 +1  
pakimd  according to pathoma, cortisol is the hormone neccessary for life. in a condition like the one presented in the Q-stem the most important hormone will be cortisol. +  


submitted by hayayah(413),

An adverse effect of doxycycline is photosensitivity.

rio19111  Why not Cipro? +1  
raspushok  Which antibiotics increase photosensitivity? Several antibiotic classes commonly cause photosensitivity, including tetracyclines (doxycycline), quinolones (ciprofloxacin, norfloxacin), and sulphonamides (trimethoprim/sulfamethoxazole, sulfasalazine). The tetracycline minocycline is not generally associated with photosensitivity. WHY not damn cipro? +  
medninja  I think it is because Cipro is not commonly used for acne treatment +  


usmleuser007  in a per-protocol analysis,[6] only patients who complete the entire clinical trial according to the protocol are counted towards the final results +1  
sympathetikey  "In an ITT population, none of the patients are excluded and the patients are analyzed according to the randomization scheme." +1  
smc213  This video helps https://www.youtube.com/watch?v=Kps3VzbykFQ +3  
rio19111  Thx smc213, really helped. +1