NBME Answers : noplanb's page

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submitted by neonem(278),

My best guess is that this patient has a bicuspid aortic valve and has a murmur due to increased volume overload from the pregnancy.

charcot_bouchard Can be congenital mild Tricuspid stenosis also. it also exaggerate during preg +

wowo probably just a flow murmur, https://acpinternist.org/weekly/archives/2017/05/16/3.htm +1

noplanb Wouldn't Tricuspid stenosis be a systolic murmur? +

noplanb I mean diastolic* +

submitted by neonem(278),

My best guess is that this patient has a bicuspid aortic valve and has a murmur due to increased volume overload from the pregnancy.

charcot_bouchard Can be congenital mild Tricuspid stenosis also. it also exaggerate during preg +

wowo probably just a flow murmur, https://acpinternist.org/weekly/archives/2017/05/16/3.htm +1

noplanb Wouldn't Tricuspid stenosis be a systolic murmur? +

noplanb I mean diastolic* +

submitted by charlie(1),

I think there's a typo on that question. MSH2 gene mutation is the culprit for HNPCC. For MHS2 gene, according to what I just searched, causes Malignant Hyperthermia Susceptibility.

noplanb Yeah I think it should be MSH +

submitted by medstruggle(7),

Why is it not ovarian follicle cells? I thought the female analog of Sertoli and Leydig is theca/granulosa cells.

colonelred_ Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen. +3

brethren_md Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +2

sympathetikey Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +2

s1q3t3 Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +2

masonkingcobra Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +1

mcl Wait, but did anyone mention that females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen??? +11

mcl But seriously though, pathology outlines says sertoli-leydig tumor "may be suspected clinically in a young patient presenting with a combination of virilization, elevated testosterone levels and ovarian / pelvic mass on imaging studies." As for follicle cell tumors, granulosa cell tumors usually occur in adults and would cause elevated levels of estrogens. Theca cell tumor would also primarily produce estrogens. Putting the links at the end since idk if they're gonna turn out right lol Link pathology outlines for sertoli leydig granulosa cell tumor theca cell tumor +6

bigjimbo LOL +

fallenistand Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen. +3

medpsychosis So after doing some intense research, UPtoDate, PubMed, an intense literature review on the topic I have come to the final conclusion that...... ...... ...... ...... Wait for it.... ..... ..... Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen. +4

charcot_bouchard Hello, i just want to add that Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +1

giggidy Hold up, so I'm confused - I read all the posts above but I still am unsure - are sertoli-leydig cells notorious for producing androgen? +1

subclaviansteele Hold the phone.....Females can get sertoli leydig cell tumors which are notorious for producing androgen? TIL TL;DR - Females can get sertoli leydig cell tumors = high androgens +

cinnapie I just found a recent study on PubMed saying "Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen" +1

youssefa Hahahahaha ya'll just bored +2

water Bored? you wouldn't think so if you knew that females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +1

nbmehelp I dont get it +

redvelvet how don't you get it that females can get Sertoli Leydig cell tumors, which are notorious for producing lots of androgen? +

drmomo what if this means..... females can get Sertoli Leydig cell tumors, which are notorious for producing lots of androgen +

sunshinesweetheart hahahaha this made my day #futurephysicians #lowkeyidiots +

sunshinesweetheart @medstruggle look up placental aromatase deficiency (p. 625 FA 2019), it would have a different presentation +

deathbystep1 i am sure i would ace STEP 1 if i only knew that females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +1

noplanb Wait... I might actually never forget this now lol +

drmohandes Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen. +1

lilmonkey Don't forget that females can get Sertoli-Leydig cell tumors, which are notorious for producing lots of androgens! You're welcome! +