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Comments ...

 +0  (nbme23#42)

To think about this simply, it literally is an obstruction so you can just choose the answer with the COPD like PFTs.

It's a bit counterintuitive that the FVC would be decreased, but the reason for this is because at the end expiration for FVC, the positive pleural pressure pushing the air out has equalized with the pressure of the atmosphere / airway wanting to keep the alveoli open. With an increase in the airway resistance from the obstruction, this equalization point comes at a higher FVC. Somebody fact check me please


 +0  (nbme23#45)

"When arterial pressure falls, myogenic tone is reduced in arterioles, decreasing their resistance to flow and maintaining capillary pressure. These observations suggest that capillary pressure may be regulated over the same range of pressure changes over which flow is autoregulated in a given organ. Indeed, from the relation:"

https://www.ncbi.nlm.nih.gov/books/NBK53445/


 +2  (nbme23#2)

https://qph.fs.quoracdn.net/main-qimg-1e53e64c8df300f79fc14781538874c4.webp

This question is asking how much reserve capacity there is of each compartment, of which the granulocytes have the least.

Note that myelosuppression can refer to any lineage (including lymphocytes).

ninja3232  This is similar to why sickle cell patients experience aplastic anemia during a parvovirus infection. +

 +0  (nbme22#45)

1) Diuretics cause metabolic alkalosis (contraction alkalosis due to hypovolemia)

2) Diarrhea in general will cause a metabolic acidosis (with NORMAL anion gap) due to loss of K+ and bicarb in the stool (stool has alkaline pH normally).

3) Therefore, laxative abuse normally causes metabolic acidosis BUT chronic abuse can result in metabolic alkalosis due to various mechanisms (response to hypovolemia + more activity of H-K ATP-ase exchanger in the collecting duct due to hypokalemia - you pee out the acid to keep more K+).





Subcomments ...

submitted by ninja3232(7),

https://qph.fs.quoracdn.net/main-qimg-1e53e64c8df300f79fc14781538874c4.webp

This question is asking how much reserve capacity there is of each compartment, of which the granulocytes have the least.

Note that myelosuppression can refer to any lineage (including lymphocytes).

ninja3232  This is similar to why sickle cell patients experience aplastic anemia during a parvovirus infection. +  
ninja3232  Sorry, this image is better. https://images.slideplayer.com/37/10733819/slides/slide_5.jpg +  


submitted by ninja3232(7),

https://qph.fs.quoracdn.net/main-qimg-1e53e64c8df300f79fc14781538874c4.webp

This question is asking how much reserve capacity there is of each compartment, of which the granulocytes have the least.

Note that myelosuppression can refer to any lineage (including lymphocytes).

ninja3232  This is similar to why sickle cell patients experience aplastic anemia during a parvovirus infection. +  
ninja3232  Sorry, this image is better. https://images.slideplayer.com/37/10733819/slides/slide_5.jpg +  


submitted by sympathetikey(1350),
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enO of het dsie fcfeets of ilpasdoCmcphoyhe is eslspuniysormope.

eSe fllu itsl fo esdi fseetcf :beolw

oissospueelrnMpy; AHicnSIFnao;D fenyi;dssrof ideomam)( heisi ocarcirsmhttyg adn leddbar redenv,taecprcn e thwi enfamrl y(yssduhl orgpu fo niadms bsne xoitc oettalim)esb ataqdeenadu hy.atndoir

ninja3232  This is incorrect. Myelosuppression can also refer to the lymphocyte lineage. +5  


submitted by ninja3232(7),

1) Diuretics cause metabolic alkalosis (contraction alkalosis due to hypovolemia)

2) Diarrhea in general will cause a metabolic acidosis (with NORMAL anion gap) due to loss of K+ and bicarb in the stool (stool has alkaline pH normally).

3) Therefore, laxative abuse normally causes metabolic acidosis BUT chronic abuse can result in metabolic alkalosis due to various mechanisms (response to hypovolemia + more activity of H-K ATP-ase exchanger in the collecting duct due to hypokalemia - you pee out the acid to keep more K+).