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Yes, he does explain very well how both cellular swelling & fat accumulation occur.
... which is exactly why this question is some chicken vs egg BS.
Everyones choice A is different.
they mean- Diffuse neutrophil infiltration
what does stellate necrotizng granuloma means ?
always with the details! losing dumb points :(
@sympathetikey Doesn't the biopsy finding vary with the biopsy location:
Lymph nodes have stellate granulomas
Bacillary Angiomatosis (skin lesion) has neutrophilic inflammation.
What do you think?
@sympathetikey Pathoma chapter 2 says cat scratch disease forms non-caseating granulomas
@ chextra Same with FA 2019 pg. 218
Immunocompetent: regional LN in axilla in one arm (like our pt here)
Immunocompromised: bacillary angiomatsis is transmitted by cat scratches
No. The order of liver damage due to alcohol is: fatty changes --> cellular swelling (cellular balooning) --> necrosis.
This Q stem states to the patient consumed large amount of alcohol on a weekend -- he has acutely drank a large amount of alcohol on one weekend --> this corresponds with fatty changes
It's not in pathoma, but I have it written in (so he or Dr. Ryan may have mentioned it) - Alcoholic hepatitis is generally seen in binge drinkers WITH A LONG HISTORY OF CONSUMPTION.
Its kind of in pathoma Chapter 1, "free radical Injury", Section 2 "examples of free radical injury" goes over how free radicals (caused by drinking) lead to fat accumulation
You can't get the steatohepatitis before getting the steatosis (fatty change).
All the FAs caused by the alcohol consumption eventually lead to cytokine release, inflammation and finally the hepatitis seen in balloon swelling.