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NBME 20 Answers

nbme20/Block 3/Question#9 (reveal difficulty score)
A 62-year-old man comes to the physician ...
Prostate ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by medschoollovin(14)
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Osteoblastic lesions are associated with prostatic adenocarcinoma mets.

Most other cancer mets to the bone are osteolytic lesions.

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submitted by โˆ—celeste(96)
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If prostate cancer spreads to other parts of the body, it nearly always goes to the bones first (cancer.org/cancer/prostate-cancer/treating/treating-pain.html)

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submitted by โˆ—chandlerbas(118)
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Legend:

OB = osteoblastic

OC = osteoclastic/osteolytic

P=prostate, B=breast, K=kidney, T=thyroid, L=lung

my mneumonic: Lead Kettle

P------------B-------------K--------------T------------L

OB-------OB/OC------OC------------OC--------OC/OB

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lilyo  @chandlerbas is this pneumonic in order of most common to least common, as in is prostate cancer the most common cause of metastasis to the bone regardless of wether the patient presents with osteoclastic or osteoblastic lesions? +
hello_planet  One addition: Breast cancer causes mixed metastases, whereas lung cancer causes either lytic or blastic depending on the cancer type. Small Cell Lung Cancer causes blastic lesions and Non-Small Cell Lung Cancer causes lytic lesions. First Aid 2019: pg. 224 +5
doublethinker  Uworld has a great Venn diagram on all the bone mets. +4



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