need help with your account or subscription? click here to email us (or see the contact page)
join telegramNEW! discord
jump to exam page:
search for anything ⋅ score predictor (โ€œpredict me!โ€)

NBME 17 Answers

nbme17/Block 4/Question#41 (reveal difficulty score)
A 45-year-old woman has a thyroidectomy ...
Calcitonin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags:

 Login (or register) to see more


 +5  upvote downvote
submitted by โˆ—cassdawg(1780)
get full access to all contentpick a username

The description of "spindle cells arranged in small cluseters" with amyloid staining as well as the mention of C-cells (which secrete calcitonin) points to a medullary thyroid carcinoma which commonly secretes calcitonin. (FA2020 p343)

Though this was not asked and not required to answer the question, she also has a history of pheochromocytoma which points to her having one of the MEN2 syndromes, as MEN2A and MEN2B are both associated with pheochromocytoma and medullary thyroid carcinoma! (FA2020 p351)

get full access to all contentpick a username



 +2  upvote downvote
submitted by โˆ—skilledboyb(20)
get full access to all contentpick a username

Typical cell marker associations in this one:

alpha fetoprotein- Hepatocellular carcinoma

hCG- choriocarcinoma or some testicular

norepinephrine- pheochromocytoma

TSH- a marker for thyroid abnormalities

get full access to all contentpick a username



Must-See Comments from nbme17

cassdawg on Membrane lipid peroxidation
cassdawg on Haemophilus influenzae type b
cassdawg on Pelvic Splanchnic
cassdawg on Actinic keratosis
cassdawg on Early septic shock
cassdawg on Epinephrine
flapjacks on Placebo effect
cassdawg on 0.9% Saline
waitingonprometric on Tubular adenoma
bingcentipede on Surface kappa:surface lambda ratio
cassdawg on Free T4
tinyhorse on 25%
cassdawg on Absence of functional LDL receptors in ...
bingcentipede on Residual volume: โ†‘; Arterial PO2: โ†“; ...

search for anything NEW!