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NBME 17 Answers

nbme17/Block 0/Question#0 (reveal difficulty score)
15-year-old, lesions on neck, acid-fast ...
Temperature Sensitivity ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—cassdawg(1780)
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Mycobacterium leprae likes cool temperatures (FA2020 p141)

Mycobacterium leprae is an acid-fast bacteria which can cause two skin manifestations:

  • Lepromatous presents diffusely over the skin and with leonine facies and is more serious with a largely Th2 response and high bacteria load
  • Tuberculoid (what our patient has) presents with a few hypoesthetic hairless skin plaques with a largely Th1 response and low bacteria load

Leprosy likes cool temperatures so it infects skin and superficial nerves. Even without knowing the organism, the link could also be potentially inferred!

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bingcentipede  In addition, the only other acid-fast bacterium is Nocardia; they would have to describe it as branching/filamentous (NOT a bacillus!). +3



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