The stem is describing bullous pemphigoid, which produces IgG antibodies hemidesmosomes. (PV is IgG antibodies aginst desmoglein-1 and desmoglein-3, in the oral mucosa).
BP produces the tense blisters that have a negative Nikolsky sign (don't rupture with rubbing). This is because they're supepidermal. Surprised they didn't ask about hemidesmosomes, but I think that that the BP antigen is part of the hemidesmosomes and recruits the autoantibodies.
i_hate_it_hereNew stem was describing Bullous pemphigoid, just never heard of BP antigen lol +3
taylor5479Same here. I have literally never heard of "bullous pemphigoid antigen" lol+
chaosawaitsFA2019 page 465: it talks about "bullous pemphigoid antibodies." Antibodies have antigens. Plus, desmoplakin and plakoglobin are components of desmosomes, which is pemphigus vulgaris.
I also almost got torn away by BP antigen though.+
submitted by โbingcentipede(356)
The stem is describing bullous pemphigoid, which produces IgG antibodies hemidesmosomes. (PV is IgG antibodies aginst desmoglein-1 and desmoglein-3, in the oral mucosa).
BP produces the tense blisters that have a negative Nikolsky sign (don't rupture with rubbing). This is because they're supepidermal. Surprised they didn't ask about hemidesmosomes, but I think that that the BP antigen is part of the hemidesmosomes and recruits the autoantibodies.